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Animal Models and New Approach Methodologies (NAMs)

July 30, 2025
NAMs are intended to expand our tools for modeling human biology and disease. While this field is rapidly evolving, the need for animal models remains since current alternative approaches cannot accurately replicate or model all biological and behavioral aspects of human disease.  Importantly, animal models serve as vital in vivo controls for the validation and verification of emerging NAMs.  NIH encourages researchers to use complementary approaches as appropriate to promote rigor and reproducibility in scientific studies. Contact the RRRC to see how we can assist with your animal needs as well as support your NAM experiments.  
05.21.2026

Weather and Shipping

The welfare of the animals is of utmost importance and as we head into the summer months, inclement weather and excessive heat will delay/prevent shipments of live animals.  Be aware that hot temperatures between June and mid-September may negatively impact the ability of couriers to safely ship animals so please plan your live animal orders accordingly.

05.21.2026

Provide Your Input on NIH's Proposed Strategic Plan by May 26, 2026.

The NIH is currently seeking input for its next strategic plan, and a major focus of this framework involves the future of animal research. Because these high-level policies directly impact the future of the RRRC and your work, it’s crucial that the scientific community participates. The NIH has provided a short feedback form that only takes a few minutes to complete. Please consider submitting your input. URL: https://grants.nih.gov/news-events/nih-extramural-nexus-news/2026/03/nih-seeks-input-on-framework-for-next-nih-wide-strategic-plan   Comments must be submitted electronically through the submission website. Responses must be received on May 26, 2026, by 11:59:59 p.m. (ET). 

07.30.2025

Animal Models and New Approach Methodologies (NAMs)

NAMs are lab (e.g., organoids and iPSCs) or computer-based methods intended to expand our tools for modeling human biology and disease. While this field is rapidly evolving, the need for animal models remains, especially for situations where a complex biological system is necessary. In addition, animal models serve as vital in vivo controls for the validation and verification of emerging NAMs.