RRRC Donate Models

Process For Submission and Acceptance of Rats



1. Donating investigators should read and agree to the terms outlined in Terms and Conditions of Strain Submission.

2. Fill out the Application Form and submit it on-line. A completed Application Form will be generated from the information you provide. It will be displayed and a copy e-mailed to you.

3. The RRRC Application Review Committee will evaluate applications and issue decisions on submitted strains. You will be notified by e-mail of the status of your strain submission within 30 days of completion of your Strain Submission Application.

4. If your strain is accepted, you will be asked to complete or provide the following:
  • MTA form
  • Breeding and Husbandry Form
  • Send genotyping protocol
  • Send phenotyping protocol if gene mutation is unknown
  • Register your strain with the Rat Genome Database (RGD)  

5. After the strain profile information is reviewed and accepted, you will be contacted by RRRC staff to discuss and coordinate the final steps involving shipping of the animals to the RRRC. At that time, you will be asked to:
  • Submit a recent Health Status Report
  • Provide RRRC Project manager with details about rats/materials available for transfer to the RRRC

6. You will work with RRRC staff to arrange shipping of animals/materials to the RRRC.  Please note that while our staff will work with you to coordinate the shipping arrangements, it is the responsibility of the donating investigator to contract an appropriate courier and cover the costs associated with shipping animals/materials to the RRRC.

02.16.2025

In Need of a New Rat Model?

Need a new rat model?  The RRRC in conjunction with the MU Animal Modeling Core (AMC) can assist with the generation of transgenic rats, create knock-out and knock-in rats using CRISPR/Cas9 technology and genetically manipulate rat embryonic stem cells to make chimeric animals.  Contact us to discuss your rat model needs and how we can help. 

07.07.2024

Laboratory Animal Genetic Reporting (LAG-R) Guidelines Published

The LAG-R framework (Laboratory Animal Genetic Reporting) is a set of guidelines to support more complete documentation of the genetic make-up of animals of all species that are used in research, with the aim of bolstering reproducibility, reliability, and overall scientific rigor. See Nature Communications (https://doi.org/10.1038/s41467-024-49439-y).

02.05.2024

GRCr8: A new rat reference assembly is now available.

GRCr8 (GenBank NCBI # GCA_036323735.1) is the latest version of the rat reference genome assembly. See the Genome Reference Consortium (GRC) blog for more details.