for assistance call: 1-888-673-3444
 
Happy World Rat Day!
 April 04, 2023
April 4, 2023 is World Rat Day!  The RRRC would like to acknowledge the important contributions to science and medicine made possible by the use of rats in biomedical research.
Exciting Job Opportunities
 April 03, 2023
The RRRC is looking to expand its team!  We have positions available in colony management, data curation, cryobiology, reproductive biology, and customer service.  We are also looking for individuals interested in post-doctoral training with both a service and research emphasis.  Interested in learning more?  Contact Dr. Elizabeth Bryda at rrrc@missouri.edu.

NIH Extrinsic Factors Workshop
 August 09, 2022

Enhance Rigor and Reproducibility in Animal Research by Managing Extrinsic Factors

When: September 23, 28, and 30, 2022

Venue: Zoom

Register: scgcorp.com/ExtrinsicFactorsWS

The workshop will be a forum to discuss the current status of and needs for understanding extrinsic environmental factors; their potential impact on animal research outcomes; and how facilities may optimally manage, monitor, and report these extrinsic factors in an effort to enhance reproducibility and rigor in animal research. The focus of this workshop will be on identifying gaps, opportunities, and new approaches in husbandry of commonly and widely used animal models; relevant environmental factors and conditions; and the need for novel instruments, equipment, and infrastructure for animal research core facilities (e.g., modern design of research core facilities, high-throughput equipment, telemetry for behavioral research).

Rats on the rise
 July 20, 2021
Rats on the rise.  Ellen P. Neff (Lab Animal, 2021). After a genetic revolution in the 80s, mice overtook rats as the laboratory animal of choice for many researchers. But in recent years, the gene editing capabilities that had lagged a little for the larger rodent have been coming up to par with their murine cousins. Is a return to rats on the way?
RRRC Fully Operational
 June 14, 2020
The RRRC is fully operational at this time and we are excited to be able to assist researchers with all their rat-related needs. 
Cryopreservation
The RRRC has continued to refine cryopreservation techniques in the rat.  Improvements to intracytoplasmic sperm injection (ICSI) now allow sperm cryopreservation for a cost effect means of archiving large collection sets of rats. 
 
Osmotic tolerance limits and effects of cryoprotectants on the motility, plasma membrane integrity and acrosomal integrity of rat sperm.
Si W, Benson JD, Men H, Critser JK. Cryobiology. 2006 Dec;53(3):336-48.

Vibration study of the Piezo-driven pipettes immersed in viscous liquids. Fan M, Agca Y, Critser JK, Feng F. Journal of Applied Physics 2006;  100(7):74701-74708.

Changes in rat spermatozoa function after cooling, cryopreservation and centrifugation processes. Kim S, Agca C, Agca Y. Cryobiology. 2012 Jun 30.