for assistance call: 1-888-673-3444
 
Microbiota Characterization Now Offered
 July 07, 2014
The RRRC now offers a full line of NGS-related services including fecal DNA extraction, 16S rDNA gene sequencing, and informatics analysis to researchers using rat models.  For more information, please see here or contact www.rrrc.us.
Need a New Rat Model?
 March 21, 2017
Need a new rat model?  The RRRC in conjunction with the MU Animal Modeling Core (AMC) can assist with the generation of transgenic rats, create knock-out and knock-in rats using CRISPR/Cas9 technology and genetically manipulate rat embryonic stem cells to make chimeric animals.  Contact us to discuss your rat model needs and how we can help.
Cryopreservation
The RRRC has continued to refine cryopreservation techniques in the rat.  Improvements to intracytoplasmic sperm injection (ICSI) now allow sperm cryopreservation for a cost effect means of archiving large collection sets of rats. 

  1.  Osmotic tolerance limits and effects of cryoprotectants on the motility, plasma membrane integrity and acrosomal integrity of rat sperm. Si W, Benson JD, Men H, Critser JK. Cryobiology. 2006 Dec;53(3):336-48.
  2. Vibration study of the Piezo-driven pipettes immersed in viscous liquids. Fan M, Agca Y, Critser JK, Feng F. Journal of Applied Physics 2006;  100(7):74701-74708.
  3. Changes in rat spermatozoa function after cooling, cryopreservation and centrifugation processes. Kim S, Agca C, Agca Y. Cryobiology. 2012 Jun 30.